Concepts of inhibition and developmental psychopathology.

Citation

Nigg, J. T., Carr, L., Martel, M., & Henderson, J. M. (2007). Concepts of inhibition and developmental psychopathology. In D. S. Gorfein & C. M. MacLeod (Eds.), Inhibition in cognition (pp. 259-277). Washington, DC, US: American Psychological Association.

http://dx.doi.org/10.1037/11587-013

Abstract

In this chapter, we review the body of work performed in our laboratory and reviewed in the literature that attempts to isolate different kinds of putative inhibitory control in relation to attention-deficit/hyperactivity disorder (ADHD) and, to a lesser extent, other forms of impulsive psychopathology. ADHD is a disorder usually identified in childhood but that is now known to also occur in adults. It is described clinically by two highly correlated but partially distinct symptom domains: inattention-disorganization (e.g., losing things, not paying attention, having difficulty staying on task) and hyperactivity-impulsivity. These domains in turn are used to define a primarily inattentive subtype (ADHD-PI), a primarily hyperactive-impulsive subtype (ADHD-PH), and a combined subtype that involves both inattention and hyperactivity-impulsivity (ADHD-CT). Another type of psychopathology that we discuss is borderline personality disorder, a syndrome marked by unstable and intense interpersonal relationships, extreme anger, fear of abandonment, and self-destructive and impulsive behavior. We also mention conduct disorder (extreme rule breaking and aggressive behavior in childhood) and antisocial personality disorder (extreme rule breaking, aggression, and indifference to the rights of others in adulthood). Finally, we mention substance use disorders (out-of-control use of alcohol or illicit drugs). We present convergent evidence using multiple approaches to suggest that in parsing psychopathology, it is important to distinguish several kinds of inhibitory control, in particular effortful versus reactive control and motor response suppression versus interference control. (PsycINFO Database Record (c) 2016 APA, all rights reserved)